Hi Ced1106. I think you need to pick and choose as the scale of the sculpts varies so wildly, as does the thickness of the pre-paint. A lot of the more recent "Heroclix" releases appear far smaller/thinner than the original releases, so I tend to avoid those, but every now and then a nice mini which matches the older scale will show up - particularly the larger models.
I tend to re-prime them to get rid of the pre-paint when I can but every now and then have to use their pre-paint as the prime and just layer instead. Hope this makes sense? :-)