IMHO you could certainly use TSATF for Seminole Wars. Depending on the size of the armies and the type of scenarios, you might want to try using "The Sword In Africa" with its more pulp/skirmish feel, and create some new "Event Cards" specific to the campaign(s), with the swamps, gators, plantations, mules, boats, etc. I don't personally know anyone who's done it before, but I'm guessing it's been done, as TSATF has been used by someone somewhere for virtually every colonial campaign from Ancient Rome vs. Gauls and Britons, to the AWI and even the 1965-1973 war in Vietnam.
On the other hand, while the Seminole Wars are well and good, personally I prefer your "The Wind And The Lion" idea, mostly because it is my favorite movie of all time!
One of the greatest games I ever played in was a refight of the action finale from The Wind And The Lion, run bye Jeff Baumal AKA: Sgt. Guiness, who frequents this site. Playing an entire Wind and the Lion campaign would be a dream come true! It could include French, Germans, the Sultanate of Moroccan, the Raisuli's Berber brigands/pirates, and of course a landing force of US Marines supported by a Navy Machine-Gun detachment! Gunboats in the harbor of Tangier... military intervention at the Bashaw's Palace... an epic battle pitting the combined troops of the Sultan & the Kaiser against Roosevelt's leathernecks and the Raisuli's warriors?!?! Oh, man -- I get chills just thinking about it!