I've played Chaos in Cairo many times and it's a great game system. It uses the goalsystem that was designed for Supersystem. (you roll a d6 for each of your attribute points and modifiers. A roll of 4+ is a success). It really is a clean system.
When I was getting into pulp I enjoyed it and .45 Adventures about equally, but preferred .45A's character creation system. CiC allowed character creation, but was more designed, IMO, for scenario's built around the included characters.
Marc