As an idea I think it has possibilities - you could use FIW terrain with 15th Century figures and bow armed natives. It would certainly have changed the dynamic of early colonisation - the Europeans would still have had the germs on their side but their other advantages might not have been so great.
Captain Blood, thanks for the heads up - I've removed anything that is a bit extraneous from the Blog. I'm a bit of a klutz technically so how to sweep it to find the offending line of code is beyond me....Unfortunately, I've never earned any cash from the blog at all!