Frostgrave is very much centered around magic users and their spells, but it is an interesting idea. I was thinking about legendary Martial Artists with a similar skillset to make them as colourful as the wizards, but I am afraid that a martial artist with lots of personal offensive capabilities would be abused as a "wizard killer". I think maybe it is worth a try (you could pit two martial artists against each other nonetheless which would lead to some climatic stand-offs).
Frostgrave is a good excuse to paint lots of peculiar miniatures from my collection so it is a good base to try out different rulesets. For a battle of the secular against the "peculiar" I want to give Daisho a try. Ronin is also a nice ruleset (I originally painted the rank & file for this game) but it is more Kurosawa than pop culture