There was a game released a few years ago called 'Patrols in the Sudan' which was. as I recall, a solo skirmish game. Haven't played it myself but I remember reading good things about it.
So certainly, at least some people find it a viable option.
Historically, the Nile Expedition doesn't offer all that much in the way of scenarios for skirmishing, but it wasn't the only campaign/theatre of that long conflict. Skirmishing around the construction of the Suakin-Berber Railway springs to mind and I'm sure others could be dreamt up with a bit of thought.