If you have molds, such as Hirst, go with Smoothcast 300. So, so easy to work with, sets in 3-5 minutes or so, and is incredibly durable. 20$ at Misterart.com, at least it was when I last ordered.
I've also used 50/50 Lightweight hydrocal/hydraulic cement and it's hard as dental stone almost, but it takes a half hour to set up.
Go to Hirstarts.com and watch the plastic casting tutorial. Its magical.